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CAMK2B 抗体 (AA 1-503)

CAMK2B 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 1050CT14-1-3 unconjugated
产品编号 ABIN6244287
发货至: 中国
  • 抗原 See all CAMK2B 抗体
    CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))
    抗原表位
    • 16
    • 15
    • 7
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    • 6
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    • 3
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 1-503
    适用
    • 72
    • 66
    • 60
    • 5
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    人, 小鼠, 大鼠
    宿主
    • 82
    • 14
    小鼠
    克隆类型
    • 82
    • 14
    单克隆
    标记
    • 46
    • 5
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    • 1
    • 1
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    • 1
    • 1
    This CAMK2B antibody is un-conjugated
    应用范围
    • 87
    • 40
    • 18
    • 14
    • 14
    • 14
    • 14
    • 7
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    • 5
    • 3
    • 2
    • 1
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This CAMK2 beta antibody is generated from a mouse immunized with a recombinant protein between 1-503 amino acids from human CAMK2 beta.
    克隆位点
    1050CT14-1-3
    亚型
    IgG1
    Top Product
    Discover our top product CAMK2B Primary Antibody
  • 应用备注
    WB: 1:2000. IHC-P: 1:25
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))
    别名
    CAMK2 beta (CAMK2B 产品)
    别名
    CAM2 antibody, CAMK2 antibody, CAMKB antibody, Camk2d antibody, Ck2b antibody, camk2 antibody, camk2b antibody, cam2 antibody, camkb antibody, CAMK2B antibody, calcium/calmodulin dependent protein kinase II beta antibody, calcium/calmodulin-dependent protein kinase II, beta antibody, calcium/calmodulin-dependent protein kinase II beta antibody, calcium/calmodulin dependent protein kinase (CaM kinase) II alpha S homeolog antibody, calcium/calmodulin dependent protein kinase (CaM kinase) II beta L homeolog antibody, calcium/calmodulin-dependent protein kinase (CaM kinase) II beta antibody, CAMK2B antibody, Camk2b antibody, camk2a.S antibody, camk2b.L antibody
    背景
    Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca(2+) transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling. Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2.
    分子量
    72678
    UniProt
    Q13554
    途径
    WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
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