This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This WDR82 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 50-85 amino acids from the N-terminal region of human WDR82.
Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.