DKK2 抗体
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- 抗原 See all DKK2 抗体
- DKK2 (Dickkopf 2 Homolog (DKK2))
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DKK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- This DKK2 antibody is generated from a mouse immunized with a recombinant protein of human DKK2.
- 克隆位点
- 1833CT856-7-20
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product DKK2 Primary Antibody
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- 应用备注
- WB: 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- DKK2 (Dickkopf 2 Homolog (DKK2))
- 别名
- DKK2 (DKK2 产品)
- 别名
- DKK-2 antibody, Dkk4 antibody, zgc:171574 antibody, dickkopf WNT signaling pathway inhibitor 2 antibody, DKK2 antibody, Dkk2 antibody, dkk2 antibody
- 背景
- Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
- 分子量
- 28447
- UniProt
- Q9UBU2
- 途径
- WNT signaling
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