This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This PRPF8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2239-2273 amino acids from the C-terminal region of human PRPF8.
Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site.