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SRGAP2 抗体 (C-Term)

SRGAP2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53245 unconjugated
产品编号 ABIN6244085
发货至: 中国
  • 抗原 See all SRGAP2 抗体
    SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))
    抗原表位
    • 2
    • 2
    • 1
    • 1
    AA 1040-1071, C-Term
    适用
    • 16
    • 11
    • 9
    人, 小鼠
    宿主
    • 15
    • 1
    克隆类型
    • 16
    多克隆
    标记
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SRGAP2 antibody is un-conjugated
    应用范围
    • 6
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SRGAP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1040-1071amino acids from the C-terminal region of human SRGAP2.
    克隆位点
    RB53245
    亚型
    Ig Fraction
    Top Product
    Discover our top product SRGAP2 Primary Antibody
  • 应用备注
    WB: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))
    别名
    SRGAP2 (SRGAP2 产品)
    别名
    ARHGAP34 antibody, FNBP2 antibody, SRGAP2A antibody, SRGAP3 antibody, 9930124L22Rik antibody, AI448945 antibody, FBP2 antibody, Fnbp2 antibody, srGAP3 antibody, AI452337 antibody, Arhgap14 antibody, D130026O08Rik antibody, Gbi antibody, MEGAP antibody, WRP antibody, mKIAA0411 antibody, RGD1566016 antibody, srGAP2 antibody, srgap2a antibody, wu:fb47h12 antibody, zgc:136814 antibody, fnbp2 antibody, srgap2 antibody, SLIT-ROBO Rho GTPase activating protein 2 antibody, SLIT-ROBO Rho GTPase activating protein 3 antibody, SLIT-ROBO Rho GTPase activating protein 2 L homeolog antibody, SRGAP2 antibody, Srgap2 antibody, Srgap3 antibody, srgap2 antibody, srgap2.L antibody
    背景
    RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. Plays an important role in different aspects of neuronal morphogenesis and migration mainly during development of the cerebral cortex. This includes the biogenesis of neurites, where it is required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. Also stimulates the branching of the leading process and negatively regulates neuron radial migration in the cerebral cortex. Its interaction and inhibition by SRGAP2C reduces the rate of spine maturation, alters dendritic spine morphology and density and indirectly increases neuronal migration. It may have implications for cognition, learning and memory. In non-neuronal cells, it may also play a role in cell migration by regulating the formation of lamellipodia and filopodia.
    分子量
    120871
    UniProt
    O75044
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