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RBMX 抗体 (AA 222-252)

This anti-RBMX antibody is a 兔 多克隆 antibody detecting RBMX in WB. Suitable for 人.
产品编号 ABIN6244062
发货至: 中国

Quick Overview for RBMX 抗体 (AA 222-252) (ABIN6244062)

抗原

See all RBMX 抗体
RBMX (RNA Binding Motif Protein, X-Linked (RBMX))

适用

  • 23
  • 10
  • 9
  • 5
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  • 3
  • 3
  • 2
  • 1
  • 1
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宿主

  • 23

克隆类型

  • 22
  • 1
多克隆

标记

  • 16
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RBMX antibody is un-conjugated

应用范围

  • 16
  • 8
  • 8
  • 5
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  • 2
  • 1
Western Blotting (WB)

克隆位点

RB53800
  • 抗原表位

    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 222-252

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This RBMX antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 222-252 amino acids from the Central region of human RBMX.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    RBMX (RNA Binding Motif Protein, X-Linked (RBMX))

    别名

    RBMX

    背景

    RNA-binding protein that plays several role in the regulation of pre- and post-transcriptional processes. Implicated in tissue-specific regulation of gene transcription and alternative splicing of several pre-mRNAs. Binds to and stimulates transcription from the tumor suppressor TXNIP gene promoter, may thus be involved in tumor suppression. When associated with SAFB, binds to and stimulates transcription from the SREBF1 promoter. Associates with nascent mRNAs transcribed by RNA polymerase II. Component of the supraspliceosome complex that regulates pre-mRNA alternative splice site selection. Can either activate or suppress exon inclusion, acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN2. Represses the splicing of MAPT/Tau exon 10. Binds preferentially to single- stranded 5'-CC[A/C]-rich RNA sequence motifs localized in a single-stranded conformation, probably binds RNA as a homodimer. Binds non-specifically to pre-mRNAs. Plays also a role in the cytoplasmic TNFR1 trafficking pathways, promotes both the IL-1- beta-mediated inducible proteolytic cleavage of TNFR1 ectodomains and the release of TNFR1 exosome-like vesicles to the extracellular compartment.

    分子量

    42332

    UniProt

    P38159

    途径

    Chromatin Binding, Ribonucleoprotein Complex Subunit Organization
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