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USP2 抗体 (AA 1-258)

USP2 适用: 人, Green Monkey WB 宿主: 小鼠 Monoclonal 1738CT331-50-87 unconjugated
产品编号 ABIN6244029
发货至: 中国
  • 抗原 See all USP2 抗体
    USP2 (Ubiquitin Specific Peptidase 2 (USP2))
    抗原表位
    • 15
    • 9
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-258
    适用
    • 65
    • 8
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, Green Monkey
    宿主
    • 62
    • 3
    小鼠
    克隆类型
    • 64
    • 1
    单克隆
    标记
    • 32
    • 7
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This USP2 antibody is un-conjugated
    应用范围
    • 47
    • 37
    • 24
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This USP2 antibody is generated from a mouse immunized with a recombinant protein between 1-258 amino acids from human USP2.
    克隆位点
    1738CT331-50-87
    亚型
    IgG1 kappa
    Top Product
    Discover our top product USP2 Primary Antibody
  • 应用备注
    WB: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    USP2 (Ubiquitin Specific Peptidase 2 (USP2))
    别名
    USP2 (USP2 产品)
    别名
    UBP41 antibody, USP9 antibody, B930035K21Rik antibody, Ubp41 antibody, UBP-t antibody, UBP46 antibody, ubp52 antibody, ubp66 antibody, zgc:92134 antibody, ubiquitin specific peptidase 2 antibody, ubiquitin specific peptidase 2a antibody, USP2 antibody, Usp2 antibody, usp2a antibody
    背景
    Hydrolase that deubiquitinates polyubiquitinated target proteins such as MDM2, MDM4 and CCND1. Isoform 1 and isoform 4 possess both ubiquitin-specific peptidase and isopeptidase activities. Deubiquitinates MDM2 without reversing MDM2-mediated p53/TP53 ubiquitination and thus indirectly promotes p53/TP53 degradation and limits p53 activity. Has no deubiquitinase activity against p53/TP53. Prevents MDM2-mediated degradation of MDM4. Plays a role in the G1/S cell-cycle progression in normal and cancer cells. Plays a role in the regulation of myogenic differentiation of embryonic muscle cells. Regulates the circadian clock by modulating its intrinsic circadian rhythm and its capacity to respond to external cues. Associates with clock proteins and deubiquitinates core clock component PER1 but does not affect its overall stability. Regulates the nucleocytoplasmic shuttling and nuclear retention of PER1 and its repressive role on the clock transcription factors CLOCK and ARNTL/BMAL1 (By similarity).
    分子量
    68072
    UniProt
    O75604
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