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TRIM24 抗体 (C-Term)

TRIM24 适用: 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB51160 unconjugated
产品编号 ABIN6244019
发货至: 中国
  • 抗原 See all TRIM24 抗体
    TRIM24 (Tripartite Motif Containing 24 (TRIM24))
    抗原表位
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 789-843, C-Term
    适用
    • 62
    • 23
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    小鼠
    宿主
    • 57
    • 5
    • 1
    克隆类型
    • 56
    • 7
    多克隆
    标记
    • 37
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TRIM24 antibody is un-conjugated
    应用范围
    • 43
    • 26
    • 13
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Mouse Trim24 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 789-843 amino acids from the C-terminal region of Mouse Trim24.
    克隆位点
    RB51160
    亚型
    Ig Fraction
    Top Product
    Discover our top product TRIM24 Primary Antibody
  • 应用备注
    IF: 1:25. WB: 1:1000. WB: 1:2000. IHC-P: 1:25
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    TRIM24 (Tripartite Motif Containing 24 (TRIM24))
    别名
    Trim24 (TRIM24 产品)
    别名
    TRIM24 antibody, PTC6 antibody, RNF82 antibody, TF1A antibody, TIF1 antibody, TIF1A antibody, TIF1ALPHA antibody, hTIF1 antibody, ptc6 antibody, rnf82 antibody, tf1a antibody, tif1 antibody, tif1a antibody, tif1alpha antibody, A130082H20Rik antibody, AI447469 antibody, D430004I05Rik antibody, TIF1-alpha antibody, TIF1alpha antibody, Tif1a antibody, tripartite motif containing 24 antibody, transcription intermediary factor 1-alpha antibody, tripartite motif containing 24 S homeolog antibody, tripartite motif-containing 24 antibody, TRIM24 antibody, trim24 antibody, LOC100548578 antibody, trim24.S antibody, Trim24 antibody
    背景
    Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac) (By similarity). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis via its effects on p53/TP53 levels. Up-regulates ligand- dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor (TR) and ESR1. Modulates transcription activation by retinoic acid (RA) receptors, such as RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes. Required for normal transition from proliferating neonatal hepatocytes to quiescent adult hepatocytes.
    分子量
    116657
    UniProt
    Q64127
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