HRBP14.4 antibody, POLRF antibody, RPABC2 antibody, RPB14.4 antibody, RPB6 antibody, 1810060D16Rik antibody, RNA polymerase II subunit F antibody, polymerase (RNA) II (DNA directed) polypeptide F antibody, POLR2F antibody, Polr2f antibody
背景
DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPB6 is part of the clamp element and together with parts of RPB1 and RPB2 forms a pocket to which the RPB4-RPB7 subcomplex binds (By similarity).