SNW1 抗体 (AA 464-497)
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- 抗原 See all SNW1 抗体
- SNW1 (SNW Domain Containing 1 (SNW1))
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抗原表位
- AA 464-497
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SNW1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This SNW1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 464-497 amino acids from human SNW1.
- 克隆位点
- RB54232
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SNW1 Primary Antibody
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- 应用备注
- IF: 1:25. WB: 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- SNW1 (SNW Domain Containing 1 (SNW1))
- 别名
- SNW1 (SNW1 产品)
- 别名
- Gle1l1 antibody, Skiip antibody, bx42 antibody, ncoa-62 antibody, prp45 antibody, prpf45 antibody, skiip antibody, skip antibody, Bx42 antibody, NCOA-62 antibody, PRPF45 antibody, Prp45 antibody, SKIIP antibody, SKIP antibody, 2310008B08Rik antibody, AW048543 antibody, NCoA-62 antibody, SNW domain containing 1 antibody, nuclear protein SkiP antibody, puff-specific protein Bx42 antibody, putative nuclear protein SkiP antibody, GLE1 RNA export mediator homolog (yeast), pseudogene 1 antibody, SNW domain containing 1 S homeolog antibody, snw1 antibody, PVX_002605 antibody, LOC5564605 antibody, Smp_105860 antibody, UREG_03916 antibody, Gle1-ps1 antibody, snw1.S antibody, SNW1 antibody, Snw1 antibody
- 背景
- Involved in transcriptional regulation. Modulates TGF- beta-mediated transcription via association with SMAD proteins, MYOD1-mediated transcription via association with PABPN1, RB1- mediated transcriptional repression, and retinoid-X receptor (RXR)- and vitamin D receptor (VDR)-dependent gene transcription in a cell line-specific manner probably involving coactivators NCOA1 and GRIP1. Is involved in NOTCH1-mediated transcriptional activation. Binds to multimerized forms of Notch intracellular domain (NICD) and is proposed to recruit transcriptional coactivators such as MAML1 to form an intermediate preactivation complex which associates with DNA-bound CBF-1/RBPJ to form a transcriptional activation complex by releasing SNW1 and redundant NOTCH1 NICD. Proposed to be involved in transcriptional activation by EBV EBNA2 of CBF-1/RBPJ-repressed promoters. Is recruited by HIV-1 Tat to Tat:P-TEFb:TAR RNA complexes and is involved in Tat transcription by recruitment of MYC, MEN1 and TRRAP to the HIV promoter. Functions as a splicing factor in pre-mRNA splicing. Is required in the specific splicing of CDKN1A pre-mRNA, the function probbaly involves the recruitment of U2AF2 to the mRNA. Is proposed to recruit PPIL1 to the spliceosome. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
- 分子量
- 61494
- UniProt
- Q13573
- 途径
- Retinoic Acid Receptor Signaling Pathway
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