This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This TIMP3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 176-210 amino acids from the C-terminal region of human TIMP3.
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.