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MAD2L2 抗体 (C-Term)

MAD2L2 适用: 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB48484 unconjugated
产品编号 ABIN6243877
发货至: 中国
  • 抗原 See all MAD2L2 抗体
    MAD2L2 (MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2))
    抗原表位
    • 15
    • 9
    • 4
    • 1
    • 1
    AA 198-231, C-Term
    适用
    • 41
    • 12
    • 11
    小鼠
    宿主
    • 40
    • 2
    克隆类型
    • 32
    • 10
    多克隆
    标记
    • 17
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAD2L2 antibody is un-conjugated
    应用范围
    • 30
    • 14
    • 14
    • 13
    • 7
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This MAD2L2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 198-231 amino acids from the C-terminal region of human MAD2L2.
    克隆位点
    RB48484
    亚型
    Ig Fraction
    Top Product
    Discover our top product MAD2L2 Primary Antibody
  • 应用备注
    IF: 1:25. WB: 1:1000. IHC-P: 1:25
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    MAD2L2 (MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2))
    别名
    MAD2L2 (MAD2L2 产品)
    别名
    mad2b antibody, 2310033C13Rik antibody, MAD2B antibody, REV7 antibody, mad2B antibody, mad2l2-A antibody, xMAD2L2 antibody, POLZ2 antibody, mad2l2 antibody, zgc:110299 antibody, mitotic arrest deficient 2 like 2 antibody, MAD2 mitotic arrest deficient-like 2 antibody, mitotic arrest deficient 2 like 2 S homeolog antibody, MAD2 mitotic arrest deficient-like 2 (yeast) antibody, si:dkey-23c22.2 antibody, mad2l2 antibody, MAD2L2 antibody, Mad2l2 antibody, mad2l2.S antibody, si:dkey-23c22.2 antibody
    背景
    Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.
    分子量
    24334
    UniProt
    Q9UI95
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