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- 抗原 See all EPH Receptor B3 (EPHB3) 抗体
- EPH Receptor B3 (EPHB3)
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抗原表位
- AA 350-382
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EPH Receptor B3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This Mouse Ephb3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 350-382 amino acids from the Central region of Mouse Ephb3.
- 克隆位点
- RB50405
- 亚型
- Ig Fraction
- Top Product
- Discover our top product EPHB3 Primary Antibody
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anti-EPH Receptor B3 (EPHB3) (AA 899-997) antibody
EPHB3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 899-997) antibodyEPHB3 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3F12 unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 899-997) antibodyEPHB3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 39-212) antibodyEPHB3 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 4A122D1 unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 650-700) antibodyEPHB3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 261-390) antibodyEPHB3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B3 (EPHB3) antibodyEPHB3 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 899-998) antibodyEPHB3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E12 unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 552-601) antibodyEPHB3 适用: 人, 犬, 马, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 29-59), (N-Term) antibodyEPHB3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1653 unconjugated
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- 应用备注
- WB: 1:500-1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- EPH Receptor B3 (EPHB3)
- 别名
- Ephb3 (EPHB3 产品)
- 别名
- tck antibody, MGC83457 antibody, EPHB3 antibody, ETK2 antibody, HEK2 antibody, TYRO6 antibody, AW456895 antibody, Cek10 antibody, Etk2 antibody, MDK5 antibody, Sek4 antibody, Tyro6 antibody, CEK10 antibody, EK10 antibody, ek3 antibody, ephb3 antibody, fc62d03 antibody, rtk3 antibody, wu:fc62d03 antibody, zek3 antibody, EPH receptor B3 antibody, EPH receptor B3 L homeolog antibody, Eph receptor B3 antibody, eph receptor B3a antibody, Eph receptor tyrosine kinase antibody, EPHB3 antibody, ephb3.L antibody, ephb3 antibody, Ephb3 antibody, ephb3a antibody
- 背景
- Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Generally has an overlapping and redundant function with EPHB2. Like EPHB2, functions in axon guidance during development regulating for instance the neurons forming the corpus callosum and the anterior commissure, 2 major interhemispheric connections between the temporal lobes of the cerebral cortex. Beside its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses. Controls other aspects of development through regulation of cell migration and positioning. This includes angiogenesis, palate development and thymic epithelium development for instance. Forward and reverse signaling through the EFNB2/EPHB3 complex also regulate migration and adhesion of cells that tubularize the urethra and septate the cloaca. Finally, plays an important role in intestinal epithelium differentiation segregating progenitor from differentiated cells in the crypt.
- 分子量
- 109662
- UniProt
- P54754
- 途径
- RTK signaling
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