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- 抗原 See all NGEF 抗体
- NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
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抗原表位
- AA 187-220, N-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NGEF antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This NGEF antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 187-220 amino acids from the N-terminal region of human NGEF.
- 克隆位点
- RB53236
- 亚型
- Ig Fraction
- Top Product
- Discover our top product NGEF Primary Antibody
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anti-Neuronal Guanine Nucleotide Exchange Factor (NGEF) (AA 612-710) antibody
NGEF 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6E7 unconjugated
anti-Neuronal Guanine Nucleotide Exchange Factor (NGEF) (AA 495-710) antibodyNGEF 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Guanine Nucleotide Exchange Factor (NGEF) (AA 669-704), (C-Term) antibodyNGEF 适用: 人 WB 宿主: 兔 Polyclonal RB53235 unconjugated
anti-Neuronal Guanine Nucleotide Exchange Factor (NGEF) (AA 429-710) antibodyNGEF 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
- 别名
- NGEF (NGEF 产品)
- 别名
- Ephexin-1 antibody, ARHGEF27 antibody, EPHEXIN antibody, Tims2 antibody, ephexin antibody, Besh3 antibody, ephexin-1 antibody, neuronal guanine nucleotide exchange factor antibody, NGEF antibody, Ngef antibody
- 背景
- Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).
- 分子量
- 82496
- UniProt
- Q8N5V2
- 途径
- Neurotrophin Signaling Pathway
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