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L3MBTL1 抗体 (AA 451-485)

L3MBTL1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB53645 unconjugated
产品编号 ABIN6243755
发货至: 中国
  • 抗原 See all L3MBTL1 抗体
    L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))
    抗原表位
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 451-485
    适用
    • 19
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    小鼠
    宿主
    • 17
    • 2
    • 1
    克隆类型
    • 18
    • 1
    • 1
    多克隆
    标记
    • 19
    • 1
    This L3MBTL1 antibody is un-conjugated
    应用范围
    • 14
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This L3MBTL1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 451-485 amino acids from the Central region of human L3MBTL1.
    克隆位点
    RB53645
    亚型
    Ig Fraction
    Top Product
    Discover our top product L3MBTL1 Primary Antibody
  • 应用备注
    WB: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))
    别名
    L3MBTL1 (L3MBTL1 产品)
    别名
    C630004G01 antibody, L3mbtl antibody, mKIAA0681 antibody, H-L(3)MBT antibody, L3MBTL antibody, ZC2HC3 antibody, dJ138B7.3 antibody, RGD1307316 antibody, l(3)mbt-like (Drosophila) antibody, L3MBTL1, histone methyl-lysine binding protein antibody, l(3)mbt-like 1 (Drosophila) antibody, L3mbtl1 antibody, L3MBTL1 antibody
    背景
    Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a 'reader' of a network of post- translational modifications. PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/HIST1H1E at 'Lys-26' (H1bK26me1 and H1bK26me2) and histone H4 at 'Lys-20' (H4K20me1 and H4K20me2), leading to condense chromatin and repress transcription. Recognizes and binds p53/TP53 monomethylated at 'Lys-382', leading to repress p53/TP53-target genes. Also recognizes and binds RB1/RB monomethylated at 'Lys-860'. Participates in the ETV6-mediated repression. Probably plays a role in cell proliferation. Overexpression induces multinucleated cells, suggesting that it is required to accomplish normal mitosis.
    分子量
    92297
    UniProt
    Q9Y468
    途径
    Chromatin Binding
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