EPH Receptor B1 抗体 (AA 374-409)
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- 抗原 See all EPH Receptor B1 (EPHB1) 抗体
- EPH Receptor B1 (EPHB1)
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抗原表位
- AA 374-409
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EPH Receptor B1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- C
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This Mouse Ephb1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 374-409 amino acids from the Central region of Mouse Ephb1.
- 克隆位点
- RB50839
- 亚型
- Ig Fraction
- Top Product
- Discover our top product EPHB1 Primary Antibody
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anti-EPH Receptor B1 (EPHB1) (AA 955-984), (C-Term) antibody
EPHB1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1648 unconjugated
anti-EPH Receptor B1 (EPHB1) (AA 221-320) antibodyEPHB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-EPH Receptor B1 (EPHB1) (pTyr594), (pTyr604) antibodyEPHB1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B1 (EPHB1) (AA 260-500) antibodyEPHB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B1 (EPHB1) (AA 485-497), (Extracellular), (N-Term) antibodyEPHB1 适用: 人, 小鼠, 大鼠 WB, IF, FACS, ICC, LCI 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B1 (EPHB1) (pTyr928) antibodyEPHB1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B1 (EPHB1) (C-Term) antibodyEPHB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B1 (EPHB1) (AA 260-500) antibodyEPHB1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B1 (EPHB1) (AA 620-1596) antibodyEPHB1 适用: 人 WB, IHC, IP 宿主: 绵羊 Polyclonal unconjugated
anti-EPH Receptor B1 (EPHB1) (C-Term) antibodyEPHB1 适用: 人 WB 宿主: 绵羊 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- EPH Receptor B1 (EPHB1)
- 别名
- Ephb1 (EPHB1 产品)
- 别名
- ELK antibody, EPHT2 antibody, Hek6 antibody, NET antibody, ephb1-a antibody, xek antibody, Xek antibody, MGC89790 antibody, EPHB1 antibody, CEK6 antibody, EK6 antibody, 9330129L11 antibody, AW488255 antibody, C130099E04Rik antibody, Cek6 antibody, ENSMUSG00000074119 antibody, Elk antibody, Elkh antibody, Net antibody, Ephb2 antibody, Erk antibody, elk antibody, EPH receptor B1 antibody, EPH receptor B1 S homeolog antibody, ephrin type-B receptor 1 antibody, Eph receptor B1 antibody, EPHB1 antibody, ephb1.S antibody, ephb1 antibody, LOC100467687 antibody, Ephb1 antibody
- 背景
- Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3. During nervous system development, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline. This probably requires repulsive interaction with EFNB2. In the adult nervous system together with EFNB3, regulates chemotaxis, proliferation and polarity of the hippocampus neural progenitors. Beside its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation. May also regulate angiogenesis. More generally, may play a role in targeted cell migration and adhesion. Upon activation by EFNB1 and probably other ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively.
- 分子量
- 109881
- UniProt
- Q8CBF3
- 途径
- RTK signaling
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