This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This DLG2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 614-648 amino acids from the Central region of human DLG2.
PPP1R58 antibody, PSD-93 antibody, PSD93 antibody, chapsyn-110 antibody, A330103J02Rik antibody, B230218P12Rik antibody, B330007M19Rik antibody, Dlgh2 antibody, Gm1197 antibody, discs, large homolog 2 (Drosophila) antibody, discs large MAGUK scaffold protein 2 antibody, dlg2 antibody, DLG2 antibody, Dlg2 antibody
背景
Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity).