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CSK 抗体 (N-Term)

Name: CSK 抗体 (N-Term)
SKU: ABIN6243612
Availability: OutOfStock

CSK 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB50568 unconjugated

Western blot analysis of lysate from mouse liver tissue lysate, using Mouse Csk Antibody (N-term) (ABIN6243612 and ABIN6577562). (CSK 抗体 (N-Term))

Immunohistochemical analysis of paraffin-embedded M. (CSK 抗体 (N-Term))

IHC (p)

2 images

产品编号 ABIN6243612

发货至: 中国

Datasheet as PDF

抗原 See all CSK 抗体

CSK (C-Src tyrosine Kinase (CSK))
抗原表位
19

16

11

10

8

8

7

5

4

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 67-101, N-Term
适用
112

56

45

5

4

3

3

2

2

2

1

1

1
小鼠
宿主
100

10

3
兔
Compatible Secondaries
克隆类型
100

12
多克隆
标记
53

9

7

7

5

4

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1
This CSK antibody is un-conjugated
应用范围
102

49

26

26

16

14

13

9

7

6

6

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

B, H, Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This Mouse Csk antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 67-101amino acids from the N-terminal region of human Mouse Csk.

克隆位点

RB50568

亚型

Ig Fraction

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anti-C-Src tyrosine Kinase (CSK) (AA 241-450) antibody
CSK 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. IHC-P: 1:25

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
抗原

CSK (C-Src tyrosine Kinase (CSK))

别名

Csk (CSK 产品)

别名

AW212630 antibody, C-terminal Src kinase antibody, c-src tyrosine kinase antibody, CSK, non-receptor tyrosine kinase antibody, CSK antibody, Csk antibody

背景

Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T- cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK (By similarity).

分子量

50716

UniProt

P41241

途径

TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events