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CSK 抗体 (N-Term)

Name: CSK 抗体 (N-Term)
SKU: ABIN6243612
Availability: OutOfStock

This anti-CSK antibody is a 兔多克隆 antibody detecting CSK in WB 和 IHC (p). Suitable for 小鼠.

Western blot analysis of lysate from mouse liver tissue lysate, using Mouse Csk Antibody (N-term) (ABIN6243612 and ABIN6577562). (CSK 抗体 (N-Term))

Immunohistochemical analysis of paraffin-embedded M. (CSK 抗体 (N-Term))

IHC (p)

2 images

产品编号 ABIN6243612

发货至: 中国

Datasheet as PDF

Quick Overview for CSK 抗体 (N-Term) (ABIN6243612)

抗原

See all CSK 抗体

CSK (C-Src tyrosine Kinase (CSK))

适用

小鼠

宿主

兔

克隆类型

多克隆

标记

This CSK antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB50568

Discover our top product CSK Primary Antibody

抗原表位
18

16

8

8

7

7

5

5

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 67-101, N-Term

预测反应

B, H, Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This Mouse Csk antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 67-101amino acids from the N-terminal region of human Mouse Csk.

亚型

Ig Fraction
anti-C-Src tyrosine Kinase (CSK) (AA 1-100) antibody
CSK 适用: 人 WB, ELISA, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3A3 unconjugated

anti-C-Src tyrosine Kinase (CSK) (C-Term) antibody
Verified CSK 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) antibody
CSK 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) antibody
CSK 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5F3 unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 243-438) antibody
CSK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 325-416) antibody
CSK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) (Ser280) antibody
CSK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 330-450) antibody
CSK 适用: 人, 小鼠 WB, IP, ICC 宿主: 小鼠 Monoclonal CSK-04 unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 241-450) antibody
CSK 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 1-200) antibody
CSK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. IHC-P: 1:25

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
抗原

CSK (C-Src tyrosine Kinase (CSK))

别名

Csk

背景

Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T- cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK (By similarity).

分子量

50716

UniProt

P41241

途径

TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events