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- 抗原 See all ITGA7 抗体
- ITGA7 (Integrin, alpha 7 (ITGA7))
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抗原表位
- AA 1149-1181, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ITGA7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This ITGA7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1149-1181 amino acids from the C-terminal region of human ITGA7.
- 克隆位点
- RB52832
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ITGA7 Primary Antibody
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- 应用备注
- WB: 1:8000. WB: 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma." in: Nature communications, Vol. 7, pp. 13568, (2018) (PubMed).
: "
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Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma." in: Nature communications, Vol. 7, pp. 13568, (2018) (PubMed).
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- 抗原
- ITGA7 (Integrin, alpha 7 (ITGA7))
- 别名
- ITGA7 (ITGA7 产品)
- 别名
- [a]7 antibody, alpha7 antibody, integrin alpha 7 antibody, integrin subunit alpha 7 antibody, Itga7 antibody, ITGA7 antibody
- 背景
- Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
- 分子量
- 128948
- UniProt
- Q13683
- 途径
- Integrin Complex
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