This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This ASH2L antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 347-382 amino acids from the Central region of human ASH2L.
Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.