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ALK 抗体 (N-Term)

ALK 适用: 人 IHC (p) 宿主: 兔 Polyclonal RB1511-1512 unconjugated
产品编号 ABIN6243478
发货至: 中国
  • 抗原 See all ALK 抗体
    ALK (Anaplastic Lymphoma Receptor tyrosine Kinase (ALK))
    抗原表位
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 14-43, N-Term
    适用
    • 8
    • 2
    宿主
    • 8
    • 2
    克隆类型
    • 6
    • 4
    多克隆
    标记
    • 10
    This ALK antibody is un-conjugated
    应用范围
    • 6
    • 5
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This ALK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14~43 amino acids from the N-terminal region of human ALK.
    克隆位点
    RB1511-1512
    亚型
    Ig Fraction
    Top Product
    Discover our top product ALK Primary Antibody
  • 应用备注
    IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Liu, Mathialagan, Lappin, Fortner, Somps, Seitis, Johnson, Hu, Matsumoto: "Crizotinib reduces the rate of dark adaptation in the rat retina independent of ALK inhibition." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 143, Issue 1, pp. 116-25, (2016) (PubMed).

  • 抗原
    ALK (Anaplastic Lymphoma Receptor tyrosine Kinase (ALK))
    别名
    ALK (ALK 产品)
    别名
    Tcrz antibody, CD246 antibody, NBLST3 antibody, ALK antibody, anaplastic lymphoma kinase antibody, anaplastic lymphoma receptor tyrosine kinase antibody, ALK receptor tyrosine kinase antibody, Alk antibody, ALK antibody
    背景
    ALK, a member of the insulin receptor subfamily of Tyr protein kinases, is an orphan receptor. It appears to play an important role in the normal development and function of the nervous system. This Type I membrane protein is expressed in brain and CNS and in the small intestine and testis, but not in normal lymphoid cells. A form of non-Hodgkin's lymphoma is characterized by a chromosomal translocation t(2,5)(p23,q35) that involves NPM1 and ALK. The protein contains 1 LDL-receptor class A domain and 2 putative MAM domains.
    分子量
    176442
    NCBI登录号
    NP_004295
    UniProt
    Q9UM73
    途径
    RTK signaling
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