GSK3 beta 抗体 (N-Term)
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- 抗原 See all GSK3 beta (GSK3b) 抗体
- GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))
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抗原表位
- AA 4-34, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GSK3 beta antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- M, Rat
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This GSK3 beta (GSK3B) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-34 amino acids from the N-terminal region of human GSK3 beta (GSK3B).
- 克隆位点
- RB03816
- 亚型
- Ig Fraction
- Top Product
- Discover our top product GSK3b Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Axl mediates tumor invasion and chemosensitivity through PI3K/Akt signaling pathway and is transcriptionally regulated by slug in breast carcinoma." in: IUBMB life, Vol. 66, Issue 7, pp. 507-18, (2014) (PubMed).
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Axl mediates tumor invasion and chemosensitivity through PI3K/Akt signaling pathway and is transcriptionally regulated by slug in breast carcinoma." in: IUBMB life, Vol. 66, Issue 7, pp. 507-18, (2014) (PubMed).
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- 抗原
- GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))
- 别名
- GSK3 beta (GSK3B) (GSK3b 产品)
- 别名
- GSK3 antibody, GSK-3 antibody, C86142 antibody, GSK-3beta antibody, 7330414F15Rik antibody, 8430431H08Rik antibody, GSK3beta antibody, fk80d11 antibody, GSK-3[b] antibody, wu:fb68h05 antibody, wu:fk80d11 antibody, gsk-3 antibody, gsk3 antibody, gsk3-beta antibody, gsk3beta antibody, xgsk-3 antibody, glycogen synthase kinase 3 beta antibody, glycogen synthase kinase 3 beta L homeolog antibody, GSK3B antibody, Gsk3b antibody, gsk3b antibody, gsk3b.L antibody
- 背景
- GSK3B, a member of the Ser/Thr protein kinase family, participates in the Wnt signaling pathway. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. GSK3B phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. The protein is inhibited when phosphorylated by AKT1 or ILK1. Expressed is detected in testis, thymus, prostate and ovary, and weakly in lung, brain and kidney.
- 分子量
- 46744
- NCBI登录号
- NP_001139628, NP_002084
- UniProt
- P49841
- 途径
- WNT signaling, Hedgehog Signaling, Fc-epsilon Receptor Signaling Pathway, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagy, BCR Signaling, Warburg Effect
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