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GSK3 beta 抗体 (N-Term)

GSK3b 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03816 unconjugated
产品编号 ABIN6243417
发货至: 中国
  • 抗原 See all GSK3 beta (GSK3b) 抗体
    GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))
    抗原表位
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 4-34, N-Term
    适用
    • 6
    • 5
    • 4
    宿主
    • 7
    • 2
    克隆类型
    • 7
    • 2
    多克隆
    标记
    • 9
    This GSK3 beta antibody is un-conjugated
    应用范围
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    M, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This GSK3 beta (GSK3B) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-34 amino acids from the N-terminal region of human GSK3 beta (GSK3B).
    克隆位点
    RB03816
    亚型
    Ig Fraction
    Top Product
    Discover our top product GSK3b Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Li, Jia, Ren, Liu, Gong, Wang, Zhang, Zhao: "Axl mediates tumor invasion and chemosensitivity through PI3K/Akt signaling pathway and is transcriptionally regulated by slug in breast carcinoma." in: IUBMB life, Vol. 66, Issue 7, pp. 507-18, (2014) (PubMed).

  • 抗原
    GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))
    别名
    GSK3 beta (GSK3B) (GSK3b 产品)
    别名
    GSK3 antibody, GSK-3 antibody, C86142 antibody, GSK-3beta antibody, 7330414F15Rik antibody, 8430431H08Rik antibody, GSK3beta antibody, fk80d11 antibody, GSK-3[b] antibody, wu:fb68h05 antibody, wu:fk80d11 antibody, gsk-3 antibody, gsk3 antibody, gsk3-beta antibody, gsk3beta antibody, xgsk-3 antibody, glycogen synthase kinase 3 beta antibody, glycogen synthase kinase 3 beta L homeolog antibody, GSK3B antibody, Gsk3b antibody, gsk3b antibody, gsk3b.L antibody
    背景
    GSK3B, a member of the Ser/Thr protein kinase family, participates in the Wnt signaling pathway. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. GSK3B phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. The protein is inhibited when phosphorylated by AKT1 or ILK1. Expressed is detected in testis, thymus, prostate and ovary, and weakly in lung, brain and kidney.
    分子量
    46744
    NCBI登录号
    NP_001139628, NP_002084
    UniProt
    P49841
    途径
    WNT signaling, Hedgehog Signaling, Fc-epsilon Receptor Signaling Pathway, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagy, BCR Signaling, Warburg Effect
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