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ULK3 抗体 (C-Term)

ULK3 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 1404CT148-89-25 unconjugated
产品编号 ABIN6243328
发货至: 中国
  • 抗原 See all ULK3 抗体
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    抗原表位
    • 14
    • 10
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 435-468, C-Term
    适用
    • 54
    • 45
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 62
    • 6
    • 2
    小鼠
    克隆类型
    • 65
    • 5
    单克隆
    标记
    • 31
    • 6
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ULK3 antibody is un-conjugated
    应用范围
    • 61
    • 40
    • 11
    • 10
    • 9
    • 6
    • 3
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This ULK3 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 435-468 amino acids from the C-terminal region of human ULK3.
    克隆位点
    1404CT148-89-25
    亚型
    IgG1 kappa
    Top Product
    Discover our top product ULK3 Primary Antibody
  • 应用备注
    IHC: 1:50. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    别名
    ULK3 (ULK3 产品)
    别名
    zgc:162196 antibody, 1200015E14Rik antibody, unc-51 like kinase 3 antibody, unc-51 like kinase 3 L homeolog antibody, unc-51-like kinase 3 antibody, ULK3 antibody, ulk3 antibody, Ulk3 antibody, ulk3.L antibody
    背景
    Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.
    分子量
    53444
    UniProt
    Q6PHR2
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