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GPR56 抗体

GPR56 适用: 人 WB 宿主: 小鼠 Monoclonal 1443CT377-65-29 unconjugated
产品编号 ABIN6243208
发货至: 中国
  • 抗原 See all GPR56 抗体
    GPR56 (G Protein-Coupled Receptor 56 (GPR56))
    适用
    • 41
    • 22
    • 5
    • 4
    • 2
    宿主
    • 36
    • 5
    小鼠
    克隆类型
    • 39
    • 2
    单克隆
    标记
    • 23
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GPR56 antibody is un-conjugated
    应用范围
    • 33
    • 18
    • 15
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB)
    免疫原
    This antibody is generated from a mouse immunized with a recombinant protein.
    克隆位点
    1443CT377-65-29
    亚型
    IgG1 kappa
    Top Product
    Discover our top product GPR56 Primary Antibody
  • 应用备注
    WB: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    GPR56 (G Protein-Coupled Receptor 56 (GPR56))
    别名
    GPR56 (GPR56 产品)
    背景
    Involved in cell adhesion and probably in cell-cell interactions. Regulates the migration of neural precursor cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basemant membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Isoforms show differences in receptor signaling, specifically in serum response element (SRE) transcriptional activation upon overexpression. Overexpression inhibits melanoma tumor growth and metastasis and, during melanoma progression, regulates VEGFA production and angiogenesis through PRKCA, unprocessed GPR56 is inhibiting and GPR56 NT is activating angiogenesis.
    分子量
    77738
    UniProt
    Q9Y653
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