(2 references)-
- 抗原 See all GAB1 抗体
- GAB1 (GRB2-Associated Binding Protein 1 (GAB1))
- 适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This GAB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- This Gab1 antibody is generated from mice immunized with a GST fusion protein encoding full length human GAB1.
- 克隆位点
- 1AT1979
- 亚型
- IgG1
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anti-GRB2-Associated Binding Protein 1 (GAB1) antibody
GAB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1AT1979 unconjugated
anti-GRB2-Associated Binding Protein 1 (GAB1) (AA 250-285) antibodyGAB1 适用: 人 WB 宿主: 兔 Polyclonal RB47324 unconjugated
anti-GRB2-Associated Binding Protein 1 (GAB1) (pTyr659) antibodyGAB1 适用: 人 DB 宿主: 兔 Polyclonal RB10842 unconjugated
anti-GRB2-Associated Binding Protein 1 (GAB1) (AA 250-285) antibodyGAB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 1 (GAB1) (pTyr659) antibodyGAB1 适用: 人 ELISA, DB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "Acquired substrate preference for GAB1 protein bestows transforming activity to ERBB2 kinase lung cancer mutants." in: The Journal of biological chemistry, Vol. 288, Issue 23, pp. 16895-904, (2013) (PubMed).
: "Role of Gab1 in UV-induced c-Jun NH2-terminal kinase activation and cell apoptosis." in: Molecular and cellular biology, Vol. 24, Issue 4, pp. 1531-9, (2004) (PubMed).
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: "Acquired substrate preference for GAB1 protein bestows transforming activity to ERBB2 kinase lung cancer mutants." in: The Journal of biological chemistry, Vol. 288, Issue 23, pp. 16895-904, (2013) (PubMed).
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- 抗原
- GAB1 (GRB2-Associated Binding Protein 1 (GAB1))
- 别名
- Gab1 (GAB1 产品)
- 别名
- AA408973 antibody, AW107238 antibody, growth factor receptor bound protein 2-associated protein 1 antibody, GRB2-associated binding protein 1 antibody, GRB2 associated binding protein 1 antibody, Gab1 antibody, GAB1 antibody
- 背景
- The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 76616
- NCBI登录号
- NP_002030, NP_997006
- UniProt
- Q13480
- 途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
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