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DNMT3A 抗体 (AA 463-497)

DNMT3A 适用: 人 WB 宿主: 兔 Polyclonal RB51574 unconjugated
产品编号 ABIN6243165
发货至: 中国
  • 抗原 See all DNMT3A 抗体
    DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
    抗原表位
    • 16
    • 16
    • 13
    • 11
    • 9
    • 8
    • 7
    • 7
    • 7
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    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 463-497
    适用
    • 133
    • 55
    • 53
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 125
    • 10
    克隆类型
    • 118
    • 17
    多克隆
    标记
    • 50
    • 11
    • 10
    • 10
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DNMT3A antibody is un-conjugated
    应用范围
    • 93
    • 59
    • 30
    • 27
    • 26
    • 15
    • 10
    • 9
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    C, M, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This DNMT3A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 463-497 amino acids from the Central region of human DNMT3A.
    克隆位点
    RB51574
    亚型
    Ig Fraction
    Top Product
    Discover our top product DNMT3A Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
    别名
    DNMT3A (DNMT3A 产品)
    别名
    DNMT3A antibody, DNMT3A2 antibody, M.HsaIIIA antibody, MmuIIIA antibody, dnmt3a1 antibody, dnmt6 antibody, DNA methyltransferase 3 alpha antibody, DNA methyltransferase 3A antibody, DNA (cytosine-5-)-methyltransferase 3 alpha b antibody, DNMT3A antibody, Dnmt3a antibody, dnmt3a antibody, dnmt3ab antibody
    背景
    Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3 (H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity.
    分子量
    101858
    UniProt
    Q9Y6K1
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