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CHST4 抗体 (C-Term)

CHST4 适用: 人 WB 宿主: 兔 Polyclonal RB52322 unconjugated
产品编号 ABIN6243109
发货至: 中国
  • 抗原 See all CHST4 抗体
    CHST4 (Carbohydrate (N-Acetylglucosamine 6-O) Sulfotransferase 4 (CHST4))
    抗原表位
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 357-390, C-Term
    适用
    • 18
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 14
    • 3
    • 3
    克隆类型
    • 18
    • 2
    多克隆
    标记
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHST4 antibody is un-conjugated
    应用范围
    • 10
    • 7
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This CHST4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 357-390 amino acids from the C-terminal region of human CHST4.
    克隆位点
    RB52322
    亚型
    Ig Fraction
    Top Product
    Discover our top product CHST4 Primary Antibody
  • 应用备注
    WB: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    CHST4 (Carbohydrate (N-Acetylglucosamine 6-O) Sulfotransferase 4 (CHST4))
    别名
    CHST4 (CHST4 产品)
    别名
    CHST4 antibody, sulfo6 antibody, chst4 antibody, GST-3 antibody, Gn6st-2 antibody, HEC-GlcNAc6ST antibody, GST3 antibody, GlcNAc6ST2 antibody, HECGLCNAC6ST antibody, LSST antibody, carbohydrate sulfotransferase 4 antibody, carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 antibody, carbohydrate (chondroitin 6/keratan) sulfotransferase 4 antibody, CHST4 antibody, chst4 antibody, Chst4 antibody
    背景
    Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within mucin-associated glycans that ultimately serve as SELL ligands. SELL ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Participates in biosynthesis of the SELL ligand sialyl 6-sulfo Lewis X on receptors SPN/CD43, GLYCAM1 and MADCAM1. Also involved in biosynthesis of SELL ligand recognized by MECA-79 antibody. Plays a central role in lymphocyte trafficking during chronic inflammation. Has a catalytic preference for core 2- branched mucin-type O-glycans. Can use GlcNAcbeta1-6[Galbeta1- 3]GalNAc-pNP (core 2), GlcNAcbeta1-6ManOMe and GlcNAcbeta1-2Man oligosaccharide structures as acceptors. Has also activity toward core 3 of GlcNAcbeta1-3GalNAc-pNP. Its substrate specificity may be influenced by its subcellular location.
    分子量
    45134
    UniProt
    Q8NCG5
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