CTCF 抗体 (AA 334-364)
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- 抗原 See all CTCF 抗体
- CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
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抗原表位
- AA 334-364
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CTCF antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This CTCF antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 334-364 amino acids from the Central region of human CTCF.
- 克隆位点
- RB53773
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CTCF Primary Antibody
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anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (AA 1-260) antibody
CTCF 适用: 人 WB, IHC, IF, ChIP, IP 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) antibodyCTCF 适用: 人 WB, ChIP-seq, CUT&RUN 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) antibodyCTCF 适用: 人, 小鼠, 大鼠, 猴 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) antibodyCTCF 适用: 人 WB, IF, ChIP, IP 宿主: 兔 Monoclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (C-Term) antibodyCTCF 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (AA 1-260) antibodyCTCF 适用: 人 WB, IHC, ELISA, ChIP 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (N-Term) antibodyCTCF 适用: 人 WB, IHC, IF, ChIP, ICC, ChIP-seq, SSA, CUT&Tag 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (N-Term) antibodyCTCF 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 猴, 马, 豚鼠, Bat, 小鸡, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (C-Term) antibodyCTCF 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) (AA 521-727) antibodyCTCF 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:2000. WB: 1:2000. IHC-P: 1:25
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
- 别名
- CTCF (CTCF 产品)
- 别名
- im:7152666 antibody, CTCF antibody, xctcf antibody, AW108038 antibody, CCCTC-binding factor antibody, CCCTC-binding factor (zinc finger protein) antibody, CTCF antibody, ctcf antibody, Ctcf antibody
- 背景
- Chromatin binding factor that binds to DNA sequence specific sites. Involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. Acts as transcriptional repressor binding to promoters of vertebrate MYC gene and BAG1 gene. Also binds to the PLK and PIM1 promoters. Acts as a transcriptional activator of APP. Regulates APOA1/C3/A4/A5 gene cluster and controls MHC class II gene expression. Plays an essential role in oocyte and preimplantation embryo development by activating or repressing transcription. Seems to act as tumor suppressor. Plays a critical role in the epigenetic regulation. Participates in the allele-specific gene expression at the imprinted IGF2/H19 gene locus. On the maternal allele, binding within the H19 imprinting control region (ICR) mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to IGF2. Plays a critical role in gene silencing over considerable distances in the genome. Preferentially interacts with unmethylated DNA, preventing spreading of CpG methylation and maintaining methylation-free zones. Inversely, binding to target sites is prevented by CpG methylation. Plays a important role in chromatin remodeling. Can dimerize when it is bound to different DNA sequences, mediating long-range chromatin looping. Mediates interchromosomal association between IGF2/H19 and WSB1/NF1 and may direct distant DNA segments to a common transcription factory. Causes local loss of histone acetylation and gain of histone methylation in the beta-globin locus, without affecting transcription. When bound to chromatin, it provides an anchor point for nucleosomes positioning. Seems to be essential for homologous X-chromosome pairing. May participate with Tsix in establishing a regulatable epigenetic switch for X chromosome inactivation. May play a role in preventing the propagation of stable methylation at the escape genes from X- inactivation. Involved in sister chromatid cohesion. Associates with both centromeres and chromosomal arms during metaphase and required for cohesin localization to CTCF sites. Regulates asynchronous replication of IGF2/H19.
- 分子量
- 82785
- UniProt
- P49711
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