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RAF1 抗体 (AA 599-628)
RAF1
适用: 人
WB, IHC (p)
宿主: 兔
Polyclonal
RB13293
unconjugated
RAF1抗体详情
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抗原
See all RAF1 抗体
RAF1
(V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
抗原表位
All epitopes for RAF1 抗体
AA 599-628
适用
All reactivities for RAF1 抗体
人
宿主
All hosts for RAF1 抗体
兔
克隆类型
All clonalities for RAF1 抗体
多克隆
标记
All conjugates for RAF1 抗体
This RAF1 antibody is un-conjugated
应用范围
All applications for RAF1 抗体
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
预测反应
B, C, M, Rat
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This RAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 599-628 amino acids from human RAF1.
克隆位点
RB13293
亚型
Ig Fraction
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Discover our top product RAF1 Primary Antibody
Alternatives
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使用细节
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应用备注
WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
有效期
6 months
RAF1目标详情
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抗原
RAF1
(V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
别名
RAF1 (RAF1 产品 )
别名
CRAF antibody, NS5 antibody, Raf-1 antibody, c-Raf antibody, c-raf antibody, craf antibody, raf1 antibody, RAF1 antibody, 6430402F14Rik antibody, AA990557 antibody, BB129353 antibody, Craf1 antibody, D830050J10Rik antibody, v-Raf antibody, raf antibody, cRaf antibody, Raf-1 proto-oncogene, serine/threonine kinase antibody, Raf-1 proto-oncogene, serine/threonine kinase a antibody, v-raf-leukemia viral oncogene 1 antibody, Raf-1 proto-oncogene, serine/threonine kinase S homeolog antibody, RAF1 antibody, Raf1 antibody, raf1a antibody, raf1 antibody, raf1.S antibody
背景
RAF1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, RAF1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration.
分子量
73052
NCBI登录号
NP_002871
UniProt
P04049
途径
MAPK Pathway , RTK signaling , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , cAMP Metabolic Process , Stem Cell Maintenance , Hepatitis C , Autophagy , Signaling of Hepatocyte Growth Factor Receptor , VEGF Signaling , BCR Signaling
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