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RAF1 抗体 (AA 599-628)

RAF1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB13293 unconjugated
产品编号 ABIN6243077
发货至: 中国
  • 抗原 See all RAF1 抗体
    RAF1 (V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
    抗原表位
    • 49
    • 46
    • 35
    • 34
    • 33
    • 31
    • 24
    • 24
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    • 15
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    • 2
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    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    AA 599-628
    适用
    • 463
    • 241
    • 168
    • 14
    • 13
    • 12
    • 12
    • 9
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 495
    • 14
    • 2
    • 2
    克隆类型
    • 473
    • 40
    多克隆
    标记
    • 206
    • 37
    • 28
    • 27
    • 17
    • 16
    • 12
    • 12
    • 12
    • 12
    • 12
    • 12
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    This RAF1 antibody is un-conjugated
    应用范围
    • 301
    • 223
    • 105
    • 104
    • 96
    • 73
    • 46
    • 31
    • 30
    • 24
    • 16
    • 11
    • 8
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    B, C, M, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This RAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 599-628 amino acids from human RAF1.
    克隆位点
    RB13293
    亚型
    Ig Fraction
    Top Product
    Discover our top product RAF1 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    RAF1 (V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
    别名
    RAF1 (RAF1 产品)
    别名
    CRAF antibody, NS5 antibody, Raf-1 antibody, c-Raf antibody, c-raf antibody, craf antibody, raf1 antibody, RAF1 antibody, 6430402F14Rik antibody, AA990557 antibody, BB129353 antibody, Craf1 antibody, D830050J10Rik antibody, v-Raf antibody, raf antibody, cRaf antibody, Raf-1 proto-oncogene, serine/threonine kinase antibody, Raf-1 proto-oncogene, serine/threonine kinase a antibody, v-raf-leukemia viral oncogene 1 antibody, Raf-1 proto-oncogene, serine/threonine kinase S homeolog antibody, RAF1 antibody, Raf1 antibody, raf1a antibody, raf1 antibody, raf1.S antibody
    背景
    RAF1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, RAF1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration.
    分子量
    73052
    NCBI登录号
    NP_002871
    UniProt
    P04049
    途径
    MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Stem Cell Maintenance, Hepatitis C, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling, BCR Signaling
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