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- 抗原 See all ARID1A 抗体
- ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
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抗原表位
- AA 1717-1750
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARID1A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This ARID1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1717-1750 amino acids from human ARID1A.
- 克隆位点
- RB53540
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ARID1A Primary Antibody
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anti-AT Rich Interactive Domain 1A (SWI-Like) (ARID1A) antibody
ARID1A 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-AT Rich Interactive Domain 1A (SWI-Like) (ARID1A) (AA 655-816) antibodyARID1A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AT Rich Interactive Domain 1A (SWI-Like) (ARID1A) (AA 1930-1964) antibodyARID1A 适用: 人 WB 宿主: 兔 Polyclonal RB53541 unconjugated
anti-AT Rich Interactive Domain 1A (SWI-Like) (ARID1A) (Internal Region) antibodyARID1A 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
- 别名
- ARID1A (ARID1A 产品)
- 别名
- B120 antibody, BAF250 antibody, BAF250a antibody, BM029 antibody, C1orf4 antibody, ELD antibody, MRD14 antibody, OSA1 antibody, P270 antibody, SMARCF1 antibody, hELD antibody, hOSA1 antibody, 1110030E03Rik antibody, Osa1 antibody, Smarcf1 antibody, ARID1A antibody, wu:fb79b07 antibody, wu:fb95g08 antibody, zgc:171438 antibody, AT-rich interaction domain 1A antibody, AT rich interactive domain 1A (SWI-like) antibody, AT rich interactive domain 1Aa (SWI-like) antibody, ARID1A antibody, Arid1a antibody, arid1a antibody, arid1aa antibody
- 背景
- Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Binds DNA non-specifically. Also involved in vitamin D- coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR- mediated transrepression of the CYP27B1 gene. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
- 分子量
- 242045
- UniProt
- O14497
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation
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