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PPID 抗体 (AA 336-370)

This anti-PPID antibody is a 兔 多克隆 antibody detecting PPID in WB, IF, FACS 和 IHC (p). Suitable for 人.
产品编号 ABIN6243007
发货至: 中国

Quick Overview for PPID 抗体 (AA 336-370) (ABIN6243007)

抗原

See all PPID 抗体
PPID (Peptidylprolyl Isomerase D (PPID))

适用

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宿主

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克隆类型

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多克隆

标记

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This PPID antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB55961
  • 抗原表位

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    AA 336-370

    预测反应

    M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Cyclophilin D antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 336-370 amino acids from the human region of human Cyclophilin D.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:25. WB: 1:2000. IHC-P: 1:25. FC: 1:25. FC: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    PPID (Peptidylprolyl Isomerase D (PPID))

    别名

    Cyclophilin D

    背景

    PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA- binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer, the function is independent of HSP90 but requires the chaperone activity. Involved in regulation of UV radiation-induced apoptosis. Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large- cell lymphoma (ALK+ ALCL) cell lines. May be involved in hepatitis C virus (HCV) replication and release.

    分子量

    40764

    UniProt

    Q08752

    途径

    Nuclear Hormone Receptor Binding
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