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Serotonin Receptor 1A 抗体 (AA 239-273)

This anti-Serotonin Receptor 1A antibody is a 兔 多克隆 antibody detecting Serotonin Receptor 1A in WB 和 FACS. Suitable for 人.
产品编号 ABIN6242991
发货至: 中国

Quick Overview for Serotonin Receptor 1A 抗体 (AA 239-273) (ABIN6242991)

抗原

See all Serotonin Receptor 1A (HTR1A) 抗体
Serotonin Receptor 1A (HTR1A)

适用

  • 49
  • 31
  • 30
  • 1
  • 1

宿主

  • 42
  • 6
  • 2

克隆类型

  • 45
  • 5
多克隆

标记

  • 24
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Serotonin Receptor 1A antibody is un-conjugated

应用范围

  • 35
  • 17
  • 14
  • 13
  • 13
  • 7
  • 5
  • 4
  • 4
  • 4
Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

RB46792
  • 抗原表位

    • 15
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 239-273

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This HTR1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 239-273 amino acids from the Central region of human HTR1A.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. FC: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    Serotonin Receptor 1A (HTR1A)

    别名

    HTR1A

    背景

    G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5- hydroxytryptamine release and in the regulation of dopamine and 5- hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.

    分子量

    46107

    UniProt

    P08908

    途径

    JAK/STAT Signaling, Synaptic Membrane, Feeding Behaviour
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