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WNK1 抗体 (AA 1848-1882)
WNK1
适用: 人
WB
宿主: 兔
Polyclonal
RB56242
unconjugated
WNK1抗体详情
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抗原
See all WNK1 抗体
WNK1
(WNK Lysine Deficient Protein Kinase 1 (WNK1))
抗原表位
All epitopes for WNK1 抗体
AA 1848-1882
适用
All reactivities for WNK1 抗体
人
宿主
All hosts for WNK1 抗体
兔
克隆类型
All clonalities for WNK1 抗体
多克隆
标记
All conjugates for WNK1 抗体
This WNK1 antibody is un-conjugated
应用范围
All applications for WNK1 抗体
Western Blotting (WB)
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This WNK1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1848-1882 amino acids from human WNK1.
克隆位点
RB56242
亚型
IgG
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Discover our top product WNK1 Primary Antibody
Alternatives
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anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (Internal Region) antibody
WNK1
适用: 人, 小鼠, 大鼠, 猴, 兔, 马, Pig, Bat, Hamster, 小鸡, Cow
ELISA, IHC, IHC (p)
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
WB: 1:2000
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
有效期
6 months
WNK1目标详情
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抗原
WNK1
(WNK Lysine Deficient Protein Kinase 1 (WNK1))
别名
WNK1 (WNK1 产品 )
别名
HSAN2 antibody, HSN2 antibody, KDP antibody, PRKWNK1 antibody, PSK antibody, p65 antibody, WNK1 antibody, kdp antibody, psk antibody, hsn2 antibody, hsan2 antibody, pha2c antibody, prkwnk1 antibody, 6430573H23Rik antibody, EG406236 antibody, Hsn2 antibody, Prkwnk1 antibody, mKIAA0344 antibody, ATWNK1 antibody, T9J14.14 antibody, T9J14_14 antibody, ZIK4 antibody, with no lysine (K) kinase 1 antibody, WNK lysine deficient protein kinase 1 antibody, WNK lysine deficient protein kinase 1 L homeolog antibody, serine/threonine-protein kinase WNK1 antibody, with no lysine (K) kinase 1 antibody, WNK1 antibody, wnk1.L antibody, wnk1 antibody, LOC100056745 antibody, Wnk1 antibody
背景
Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide- sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L.
分子量
250794
UniProt
Q9H4A3
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