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Reticulon 4 抗体 (AA 28-58)

RTN4 适用: 人 WB 宿主: 兔 Polyclonal RB54371 unconjugated
产品编号 ABIN6242947
发货至: 中国
  • 抗原 See all Reticulon 4 (RTN4) 抗体
    Reticulon 4 (RTN4)
    抗原表位
    • 16
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-58
    适用
    • 68
    • 49
    • 38
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 65
    • 3
    • 3
    • 2
    • 2
    克隆类型
    • 62
    • 13
    多克隆
    标记
    • 35
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Reticulon 4 antibody is un-conjugated
    应用范围
    • 64
    • 28
    • 27
    • 21
    • 18
    • 17
    • 17
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    M, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This RTN4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 28-58 amino acids from human RTN4.
    克隆位点
    RB54371
    亚型
    Ig Fraction
    Top Product
    Discover our top product RTN4 Primary Antibody
  • 应用备注
    WB: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    Reticulon 4 (RTN4)
    别名
    RTN4 (RTN4 产品)
    背景
    Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex (By similarity). Isoform 2 reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to their change in subcellular location, from the mitochondria to the endoplasmic reticulum, after binding and sequestration. Isoform 2 and isoform 3 inhibit BACE1 activity and amyloid precursor protein processing.
    分子量
    129931
    UniProt
    Q9NQC3
    途径
    Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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