PPP6C 抗体 (C-Term)
(1 reference)-
- 抗原 See all PPP6C 抗体
- PPP6C (Protein Phosphatase 6, Catalytic Subunit (PPP6C))
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抗原表位
- AA 275-305, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PPP6C antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- M, Rat
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This PPP6C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-305 amino acids from the C-terminal region of human PPP6C.
- 克隆位点
- RB5867
- 亚型
- Ig Fraction
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anti-Protein Phosphatase 6, Catalytic Subunit (PPP6C) (AA 40-211), (Catalytic Subunit) antibody
PPP6C 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 6, Catalytic Subunit (PPP6C) (AA 1-305) antibodyPPP6C 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 6, Catalytic Subunit (PPP6C) (AA 90-139) antibodyPPP6C 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 小鸡, 犬, 豚鼠, 马, 兔, 非洲爪蟾, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 6, Catalytic Subunit (PPP6C) (AA 1-305) antibodyPPP6C 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-Protein Phosphatase 6, Catalytic Subunit (PPP6C) antibodyPPP6C 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Protein Phosphatase 6, Catalytic Subunit (PPP6C) (AA 1-30), (N-Term) antibodyPPP6C 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5866 unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers." in: eLife, Vol. 3, pp. e01695, (2014) (PubMed).
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: "Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers." in: eLife, Vol. 3, pp. e01695, (2014) (PubMed).
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- 抗原
- PPP6C (Protein Phosphatase 6, Catalytic Subunit (PPP6C))
- 别名
- PPP6C (PPP6C 产品)
- 别名
- PP6 antibody, PP6C antibody, 2310003C10Rik antibody, zgc:56227 antibody, ppp6c antibody, PPP6C antibody, pp6 antibody, MGC114734 antibody, DDBDRAFT_0168786 antibody, DDBDRAFT_0185210 antibody, DDB_0168786 antibody, DDB_0185210 antibody, CG12217 antibody, DmPpV-6A antibody, Dmel\\CG12217 antibody, PPPV6A antibody, PPV antibody, PPV 6A antibody, Ppv antibody, dPP6 antibody, protein phosphatase 6 catalytic subunit antibody, protein phosphatase 6, catalytic subunit antibody, protein phosphatase 6, catalytic subunit L homeolog antibody, serine/threonine-protein phosphatase 6 catalytic subunit antibody, Protein phosphatase V antibody, PPP6C antibody, Ppp6c antibody, ppp6c antibody, ppp6c.L antibody, ppp6C antibody, PpV antibody
- 背景
- PPP6C belongs to the PPP phosphatase family, PP-V subfamily. Reversible phosphorylation of proteins on serine and threonine residues is an important biochemical event that regulates a broad variety of intracellular processes. The phosphorylation state is determined by the well-controlled balance of activities of serine/threonine-specific protein kinases and protein phosphatases, including PPP6C. Expression levels are highest in testis, heart, and skeletal muscle and lowest in placenta, lung, and kidney. PPP6C can complement mutations in the S. cerevisiae Sit4 and S. pombe ppe1 genes, indicating that PPP6C is the functional homolog of yeast Sit4p and ppe1. Since Sit4p is required for the G1 to S transition of the cell cycle and ppe1 is involved in cell shape control and mitotic division, it has been suggested that PPP6C functions in cell cycle regulation.
- 分子量
- 35144
- NCBI登录号
- NP_001116827, NP_001116841, NP_002712
- UniProt
- O00743
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