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KCNMA1 抗体 (AA 118-152)
KCNMA1
适用: 人
WB
宿主: 兔
Polyclonal
RB53642
unconjugated
KCNMA1抗体详情
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抗原
See all KCNMA1 抗体
KCNMA1
(Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1))
抗原表位
All epitopes for KCNMA1 抗体
AA 118-152
适用
All reactivities for KCNMA1 抗体
人
宿主
All hosts for KCNMA1 抗体
兔
克隆类型
All clonalities for KCNMA1 抗体
多克隆
标记
All conjugates for KCNMA1 抗体
This KCNMA1 antibody is un-conjugated
应用范围
All applications for KCNMA1 抗体
Western Blotting (WB)
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This KCNMA1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 118-152 amino acids from human KCNMA1.
克隆位点
RB53642
亚型
Ig Fraction
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Discover our top product KCNMA1 Primary Antibody
Alternatives
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anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (C-Term) antibody
KCNMA1
适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 兔, 犬, 马, 豚鼠, 绵羊
WB, IHC
宿主: 兔
Polyclonal
unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1080-1129) antibody
KCNMA1
适用: 人, 大鼠, 小鼠, Cow, 兔, 马, 豚鼠, 绵羊, 小鸡, 非洲爪蟾, 猴, Pig, Bat
WB, IHC, IHC (p)
宿主: 兔
Polyclonal
unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1184-1200), (C-Term), (Intracellular) antibody
KCNMA1
适用: 人, 大鼠, 小鼠
WB, IHC, IF, IP, ICC
宿主: 兔
Polyclonal
unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 641-690) antibody
KCNMA1
适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 兔, 犬, 马, 豚鼠, 绵羊, 猴, Pig, Bat
WB
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
WB: 1:500
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
有效期
6 months
KCNMA1目标详情
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抗原
KCNMA1
(Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1))
别名
KCNMA1 (KCNMA1 产品 )
别名
BKTM antibody, KCa1.1 antibody, MaxiK antibody, SAKCA antibody, SLO antibody, SLO-ALPHA antibody, SLO1 antibody, bA205K10.1 antibody, mSLO1 antibody, DDBDRAFT_0190653 antibody, DDBDRAFT_0235401 antibody, DDB_0190653 antibody, DDB_0235401 antibody, KCNMA antibody, KCNMA1 antibody, 5730414M22Rik antibody, BKCa antibody, Slo antibody, Slo1 antibody, mSlo antibody, mSlo1 antibody, KCNMA1b antibody, KCNMA1c antibody, Kcnma antibody, bktm antibody, kcnma1-A antibody, sakca antibody, cSlo antibody, slo1 antibody, kcnma1 antibody, si:ch211-39f22.2 antibody, BcDNA:GH10751 antibody, CG10693 antibody, Dmel\CG10693 antibody, Dslo antibody, dSlo antibody, dSlo1 antibody, dslo antibody, fSlo antibody, potassium calcium-activated channel subfamily M alpha 1 antibody, calcium-activated BK potassium channel, alpha subunit antibody, potassium large conductance calcium-activated channel, subfamily M, alpha member 1 antibody, potassium calcium-activated channel subfamily M alpha 1 L homeolog antibody, potassium large conductance calcium-activated channel, subfamily M, alpha member 1a antibody, calcium-activated potassium channel subunit alpha-1 antibody, slowpoke antibody, KCNMA1 antibody, kcnma1 antibody, Kcnma1 antibody, kcnma1.L antibody, kcnma1a antibody, LOC100454095 antibody, slo antibody
背景
Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. In smooth muscles, its activation by high level of Ca(2+), caused by ryanodine receptors in the sarcoplasmic reticulum, regulates the membrane potential. In cochlea cells, its number and kinetic properties partly determine the characteristic frequency of each hair cell and thereby helps to establish a tonotopic map. Kinetics of KCNMA1 channels are determined by alternative splicing, phosphorylation status and its combination with modulating beta subunits. Highly sensitive to both iberiotoxin (IbTx) and charybdotoxin (CTX).
分子量
137560
UniProt
Q12791
途径
Regulation of Hormone Metabolic Process , Sensory Perception of Sound
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