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CYLD 抗体 (AA 305-582)

Name: CYLD 抗体 (AA 305-582)
SKU: ABIN6242844
Availability: OutOfStock

CYLD 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1667CT857-3-6-1 unconjugated

Anti-CYLD Antibody at 1:4000 dilution + Hela whole cell lysate Lysates/proteins at 20 μg per lane. (CYLD 抗体 (AA 305-582))

Overlay histogram showing Hela cells stained with (ABIN6242844 and ABIN6577191)(green line). (CYLD 抗体 (AA 305-582))

FACS

2 images

产品编号 ABIN6242844

发货至: 中国

Datasheet as PDF

抗原 See all CYLD 抗体

CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
抗原表位
15

7

5

2

2

1

1

1

1

1

1

1

1

1
AA 305-582
适用
43

22

17

1

1

1

1

1

1

1

1
人
宿主
38

5

1
小鼠
Compatible Secondaries
克隆类型
39

5
单克隆
标记
20

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CYLD antibody is un-conjugated
应用范围
30

14

7

5

4

3

3

3

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS)

纯化方法

This antibody is purified through a protein G column, followed by dialysis against PBS.

免疫原

This CYLD antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 305-582 amino acids from human CYLD.

克隆位点

1667CT857-3-6-1

亚型

IgG2a kappa

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anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 654-953) antibody
CYLD 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (C-Term) antibody
CYLD 适用: 人, 小鼠 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 204-358) antibody
CYLD 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5F7F4 unconjugated

anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (pSer418) antibody
CYLD 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 269-435), (C-Term) antibody
CYLD 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 32-45) antibody
CYLD 适用: 人, 小鼠, Hamster, 豚鼠, 马, 猴, 小鸡, 兔, Cow, 犬 WB, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 854-953) antibody
CYLD 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3A9 unconjugated

anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 854-953) antibody
CYLD 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2C3 unconjugated

anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (C-Term) antibody
CYLD 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:4000. FC: 1:25

限制

仅限研究用
状态

Liquid

缓冲液

Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
抗原

CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

别名

CYLD (CYLD 产品)

别名

BRSS antibody, CDMT antibody, CYLD1 antibody, CYLDI antibody, EAC antibody, MFT antibody, MFT1 antibody, SBS antibody, TEM antibody, USPL2 antibody, 2010013M14Rik antibody, 2900009M21Rik antibody, C130039D01Rik antibody, mKIAA0849 antibody, cyld antibody, LRRGT00003 antibody, Rp1 antibody, Rp1h antibody, CYLD lysine 63 deubiquitinase antibody, cylindromatosis (turban tumor syndrome), a antibody, CYLD antibody, Cyld antibody, cylda antibody

背景

Protease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Has endodeubiquitinase activity. Plays an important role in the regulation of pathways leading to NF-kappa-B activation (PubMed:< a href="http://www.uniprot.org/citations/12917689" target="_blank">12917689, PubMed:< a href="http://www.uniprot.org/citations/12917691" target="_blank">12917691). Contributes to the regulation of cell survival, proliferation and differentiation via its effects on NF-kappa-B activation (PubMed:< a href="http://www.uniprot.org/citations/12917690" target="_blank">12917690). Negative regulator of Wnt signaling (PubMed:< a href="http://www.uniprot.org/citations/20227366" target="_blank">20227366). Inhibits HDAC6 and thereby promotes acetylation of alpha-tubulin and stabilization of microtubules (PubMed:< a href="http://www.uniprot.org/citations/19893491" target="_blank">19893491). Plays a role in the regulation of microtubule dynamics, and thereby contributes to the regulation of cell proliferation, cell polarization, cell migration, and angiogenesis (PubMed:< a href="http://www.uniprot.org/citations/18222923" target="_blank">18222923, PubMed:< a href="http://www.uniprot.org/citations/20194890" target="_blank">20194890). Required for normal cell cycle progress and normal cytokinesis (PubMed:< a href="http://www.uniprot.org/citations/17495026" target="_blank">17495026, PubMed:< a href="http://www.uniprot.org/citations/19893491" target="_blank">19893491). Inhibits nuclear translocation of NF-kappa-B. Plays a role in the regulation of inflammation and the innate immune response, via its effects on NF-kappa-B activation (PubMed:< a href="http://www.uniprot.org/citations/18636086" target="_blank">18636086). Dispensable for the maturation of intrathymic natural killer cells, but required for the continued survival of immature natural killer cells. Negatively regulates TNFRSF11A signaling and osteoclastogenesis (By similarity). Involved in the regulation of ciliogenesis, allowing ciliary basal bodies to migrate and dock to the plasma membrane, this process does not depend on NF-kappa-B activation (By similarity).

分子量

107316

UniProt

Q9NQC7

途径

Apoptosis, Activation of Innate immune Response