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PI4KB 抗体 (N-Term)

PI4KB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1676 unconjugated
产品编号 ABIN6242814
发货至: 中国
  • 抗原 See all PI4KB 抗体
    PI4KB (Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB))
    抗原表位
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-51, N-Term
    适用
    • 24
    • 7
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 22
    • 2
    克隆类型
    • 22
    • 2
    多克隆
    标记
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PI4KB antibody is un-conjugated
    应用范围
    • 15
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    B, M, Rat
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This PI4KCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-51 amino acids from the N-terminal region of human PI4KCB.
    克隆位点
    RB1676
    亚型
    Ig Fraction
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Spickler, Lippens, Laberge, Desmeules, Bellavance, Garneau, Guo, Hucke, Leyssen, Neyts, Vaillancourt, Décor, OMeara, Franti, Gauthier: "Phosphatidylinositol 4-kinase III beta is essential for replication of human rhinovirus and its inhibition causes a lethal phenotype in vivo." in: Antimicrobial agents and chemotherapy, Vol. 57, Issue 7, pp. 3358-68, (2013) (PubMed).

  • 抗原
    PI4KB (Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB))
    别名
    PI4KCB (PI4KB 产品)
    别名
    PIK4CB antibody, NV15725 antibody, PI4K-beta antibody, PI4Kbeta antibody, pik4cb antibody, NPIK antibody, PI4K-BETA antibody, PI4K92 antibody, PI4KBETA antibody, PI4KIIIBETA antibody, Pik4cb antibody, zgc:152715 antibody, AA437822 antibody, ESTM41 antibody, phosphatidylinositol 4-kinase, catalytic, beta antibody, phosphatidylinositol 4-kinase beta antibody, phosphatidylinositol 4-kinase, catalytic, beta L homeolog antibody, PI4KB antibody, LOC100115953 antibody, pi4kb antibody, Pi4kb antibody, pi4kb.L antibody
    背景
    Phosphoinositides are pivotal precursors to important second messengers and as signaling and molecules. Phosphatidylinositol 4-kinases (PI4Ks) are are crucial regulators of the phosphoinsitide cascade. PI4KCB is a wortmannin-sensitive PI 4-kinase responsible for regulating the synthesis of agonist-sensitive pools of polyphosphoinositides. The cellular reservoir of PI4KCB is predominantly cytosolic, however the protein is is activated strongly by recruitment to the membrane to stimulate phosphatidylinositol 4,5-bisphosphate synthesis at the plasma membrane. PI4KCB contains an N-terminal lipid kinase unique domain, which is shared by members of both the PI3 kinase and PI4 kinase families, and a C-terminal catalytic domain, which defines this protein as a member of a much larger protein/lipid kinase family.
    分子量
    91379
    NCBI登录号
    NP_001185702, NP_001185703, NP_001185704, NP_002642
    UniProt
    Q9UBF8
    途径
    Inositol Metabolic Process
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