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UNC5B 抗体 (AA 507-541)

This anti-UNC5B antibody is a 兔 多克隆 antibody detecting UNC5B in WB. Suitable for 小鼠 和 大鼠.
产品编号 ABIN6242756
发货至: 中国

Quick Overview for UNC5B 抗体 (AA 507-541) (ABIN6242756)

抗原

See all UNC5B 抗体
UNC5B (Netrin receptor UNC5B (UNC5B))

适用

  • 37
  • 27
  • 21
  • 3
  • 3
小鼠, 大鼠

宿主

  • 33
  • 3
  • 2

克隆类型

  • 36
  • 2
多克隆

标记

  • 10
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This UNC5B antibody is un-conjugated

应用范围

  • 26
  • 14
  • 13
  • 13
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB52980
  • 抗原表位

    • 15
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 507-541

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This UNC5B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 507-541 amino acids from the Central region of human UNC5B.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    UNC5B (Netrin receptor UNC5B (UNC5B))

    别名

    UNC5B

    背景

    Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Mediates apoptosis by activating DAPK1. In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity.

    分子量

    103638

    UniProt

    Q8IZJ1
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