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- 抗原 See all PCGF1 抗体
- PCGF1 (Polycomb Group Ring Finger 1 (PCGF1))
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抗原表位
- AA 117-151
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PCGF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- B
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This PCGF1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 117-151 amino acids from the Central region of human PCGF1.
- 克隆位点
- RB51308
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PCGF1 Primary Antibody
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anti-Polycomb Group Ring Finger 1 (PCGF1) (AA 113-187) antibody
PCGF1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Polycomb Group Ring Finger 1 (PCGF1) (AA 105-187) antibodyPCGF1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Polycomb Group Ring Finger 1 (PCGF1) (AA 1-247) antibodyPCGF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Polycomb Group Ring Finger 1 (PCGF1) (AA 20-259) antibodyPCGF1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Polycomb Group Ring Finger 1 (PCGF1) (AA 121-220) antibodyPCGF1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Polycomb Group Ring Finger 1 (PCGF1) (AA 132-167) antibodyPCGF1 适用: 人 WB 宿主: 兔 Polyclonal RB51309 unconjugated
anti-Polycomb Group Ring Finger 1 (PCGF1) (AA 143-192) antibodyPCGF1 适用: 人, 小鼠, 大鼠, Pig, 兔, Cow, 斑马鱼, 犬, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- PCGF1 (Polycomb Group Ring Finger 1 (PCGF1))
- 别名
- PCGF1 (PCGF1 产品)
- 别名
- PCGF1 antibody, 2010002K04Rik antibody, NSPC1 antibody, RNF3A-2 antibody, RNF68 antibody, AU024121 antibody, Nspc1 antibody, nspc1 antibody, si:zc207o21.2 antibody, polycomb group ring finger 1 antibody, polycomb group ring finger 1 L homeolog antibody, PCGF1 antibody, pcgf1 antibody, Pcgf1 antibody, pcgf1.L antibody
- 背景
- Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin- dependent kinase inhibitor, CDKN1A. Transcriptional repressor that may be targeted to the DNA by BCL6, this transcription repressor activity may be related to PKC signaling pathway. Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). Promotes cell cycle progression and enhances cell proliferation as well. May have a positive role in tumor cell growth by down- regulating CDKN1A. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
- 分子量
- 30346
- UniProt
- Q9BSM1
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