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DKK1 抗体 (AA 1-266)

This anti-DKK1 antibody is a 兔 多克隆 antibody detecting DKK1 in WB, IHC (p) 和 IF. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6242718
发货至: 中国

Quick Overview for DKK1 抗体 (AA 1-266) (ABIN6242718)

抗原

See all DKK1 抗体
DKK1 (Dickkopf Homolog 1 (DKK1))

适用

  • 128
  • 41
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人, 大鼠, 小鼠

宿主

  • 117
  • 27
  • 2
  • 1
  • 1
  • 1

克隆类型

  • 108
  • 41
多克隆

标记

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This DKK1 antibody is un-conjugated

应用范围

  • 101
  • 54
  • 49
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  • 13
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  • 4
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  • 3
  • 1
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

克隆位点

RB52126
  • 抗原表位

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    • 1
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    AA 1-266

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This DKK1 antibody is generated from a rabbit immunized with a recombinant protein of human DKK1.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:25. WB: 1:1000. WB: 1:2000. WB: 1:4000. WB: 1:2000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    DKK1 (Dickkopf Homolog 1 (DKK1))

    别名

    DKK1

    背景

    Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

    分子量

    28672

    UniProt

    O94907

    途径

    WNT signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation
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