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DKK1 抗体 (AA 1-266)
DKK1
适用: 人, 大鼠, 小鼠
WB, IHC (p), IF
宿主: 兔
Polyclonal
RB52126
unconjugated
DKK1抗体详情
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抗原
See all DKK1 抗体
DKK1
(Dickkopf Homolog 1 (DKK1))
抗原表位
All epitopes for DKK1 抗体
AA 1-266
适用
All reactivities for DKK1 抗体
人, 大鼠, 小鼠
宿主
All hosts for DKK1 抗体
兔
克隆类型
All clonalities for DKK1 抗体
多克隆
标记
All conjugates for DKK1 抗体
This DKK1 antibody is un-conjugated
应用范围
All applications for DKK1 抗体
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This DKK1 antibody is generated from a rabbit immunized with a recombinant protein of human DKK1.
克隆位点
RB52126
亚型
Ig Fraction
Alternatives
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使用细节
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应用备注
IF: 1:25. WB: 1:1000. WB: 1:2000. WB: 1:4000. WB: 1:2000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
有效期
6 months
DKK1目标详情
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抗原
DKK1
(Dickkopf Homolog 1 (DKK1))
别名
DKK1 (DKK1 产品 )
别名
DKK-1 antibody, SK antibody, AI414495 antibody, SGY antibody, SGY-1 antibody, SGY1 antibody, Soggy antibody, mSgy antibody, dkk1 antibody, dkk antibody, dkk-1 antibody, xdkk1 antibody, Xdkk-1 antibody, Dickkopf1 antibody, dickkopf-1 antibody, mdkk-1 antibody, dkk1-A antibody, dickkopf WNT signaling pathway inhibitor 1 antibody, dickkopf like acrosomal protein 1 antibody, dickkopf-related protein 1 antibody, dickkopf-like 1 antibody, dickkopf WNT signaling pathway inhibitor 1b antibody, dickkopf protein antibody, dickkopf WNT signaling pathway inhibitor 1 S homeolog antibody, DKK1 antibody, Dkk1 antibody, DKKL1 antibody, LOC100228789 antibody, Dkkl1 antibody, dkk1b antibody, dkk1 antibody, dickkopf antibody, dkk1.S antibody
背景
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
分子量
28672
UniProt
O94907
途径
WNT signaling , Regulation of Muscle Cell Differentiation , Positive Regulation of fat Cell Differentiation
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