This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This TPM3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 245-276 amino acids from the human region of human TPM3.
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.