电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CREB3 抗体 (C-Term)

CREB3 适用: 人 WB 宿主: 兔 Polyclonal RB50244 unconjugated
产品编号 ABIN6242675
发货至: 中国
  • 抗原 See all CREB3 抗体
    CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))
    抗原表位
    • 13
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 311-344, C-Term
    适用
    • 40
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 36
    • 3
    • 1
    克隆类型
    • 37
    • 3
    多克隆
    标记
    • 23
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CREB3 antibody is un-conjugated
    应用范围
    • 31
    • 18
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This CREB3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 311-344 amino acids from the C-terminal region of human CREB3.
    克隆位点
    RB50244
    亚型
    Ig Fraction
    Top Product
    Discover our top product CREB3 Primary Antibody
  • 应用备注
    WB: 1:8000. WB: 1:8000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))
    别名
    CREB3 (CREB3 产品)
    别名
    LUMAN antibody, LZIP antibody, AU044960 antibody, AW538053 antibody, C80076 antibody, LZIP-1 antibody, LZIP-2 antibody, Luman antibody, creb3 antibody, luman antibody, lzip antibody, cAMP responsive element binding protein 3 antibody, cAMP responsive element binding protein 3 S homeolog antibody, CREB3 antibody, Creb3 antibody, creb3.S antibody
    背景
    Endoplasmic reticulum (ER)-bound transcription factor that plays a role in the unfolded protein response (UPR). Involved in cell proliferation and migration, tumor suppression and inflammatory gene expression. Plays also a role in the human immunodeficiency virus type 1 (HIV-1) virus protein expression and in the herpes simplex virus-1 (HSV-1) latent infection and reactivation from latency. Isoform 2 plays a role in the unfolded protein response (UPR). Isoform 2 acts as a positive regulator of LKN-1/CCL15-induced chemotaxis signaling of leukocyte cell migration. Isoform 2 may play a role as a cellular tumor suppressor that is targeted by the hepatitis C virus (HSV) core protein. Isoform 2 represses the VP16-mediated transactivation of immediate early genes of the HSV-1 virus by sequestring host cell factor-1 HCFC1 in the ER membrane of sensory neurons, thereby preventing the initiation of the replicative cascade leading to latent infection. Isoform 3 functions as a negative transcriptional regulator in ligand-induced transcriptional activation of the glucocorticoid receptor NR3C1 by recruiting and activating histone deacetylases (HDAC1, HDAC2 and HDAC6). Isoform 3 decreases the acetylation level of histone H4. Isoform 3 does not promote the chemotactic activity of leukocyte cells.
    分子量
    41379
    UniProt
    O43889
    途径
    Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Maintenance of Protein Location, Unfolded Protein Response
You are here:
客服