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- 抗原 See all TYRO3 抗体
- TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))
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抗原表位
- AA 854-878, C-Term
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TYRO3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This TYRO3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 854-878 amino acids from the C-terminal region of human TYRO3.
- 克隆位点
- RB50580
- 亚型
- Ig Fraction
- Top Product
- Discover our top product TYRO3 Primary Antibody
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anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibody
TYRO3 适用: 人 WB, IHC, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 2C4 unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibodyTYRO3 适用: 人 WB, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal 5B4 unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibodyTYRO3 适用: 人 WB, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal 4C8 unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 50-150) antibodyTYRO3 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 4F6 unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 728-873) antibodyTYRO3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 1-890) antibodyTYRO3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibodyTYRO3 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibodyTYRO3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1-00E-12 unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 138-321) antibodyTYRO3 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 6D6F10 unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 842-873), (C-Term) antibodyTYRO3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1489 unconjugated
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- 应用备注
- WB: 1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))
- 别名
- TYRO3 (TYRO3 产品)
- 别名
- TYRO3 antibody, brt antibody, byk antibody, dtk antibody, rse antibody, sky antibody, tif antibody, Xksy antibody, MGC145734 antibody, DKFZp469I0432 antibody, LOC100231598 antibody, BYK antibody, Dtk antibody, RSE antibody, Sky antibody, Tif antibody, Brt antibody, REK antibody, ksy antibody, xksy antibody, AI323366 antibody, Etk-2 antibody, Rse antibody, TYRO3 protein tyrosine kinase antibody, TYRO3 protein tyrosine kinase L homeolog antibody, TYRO3 protein tyrosine kinase 3 antibody, TYRO3 antibody, tyro3 antibody, Tyro3 antibody, tyro3.L antibody
- 背景
- Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with PIK3R1 and thereby enhances PI3-kinase activity. Activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 signaling plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation and cytoskeleton reorganization. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.
- 分子量
- 96905
- UniProt
- Q06418
- 途径
- RTK signaling
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