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PDCD6 抗体 (AA 103-137)

PDCD6 适用: 小鼠 WB 宿主: 兔 Polyclonal RB49787 unconjugated
产品编号 ABIN6242573
发货至: 中国
  • 抗原 See all PDCD6 抗体
    PDCD6 (Programmed Cell Death 6 (PDCD6))
    抗原表位
    • 14
    • 7
    • 6
    • 1
    • 1
    • 1
    AA 103-137
    适用
    • 48
    • 11
    • 10
    小鼠
    宿主
    • 46
    • 2
    克隆类型
    • 46
    • 2
    多克隆
    标记
    • 15
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PDCD6 antibody is un-conjugated
    应用范围
    • 30
    • 27
    • 12
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This PDCD6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 103-137 amino acids from the Central region of human PDCD6.
    克隆位点
    RB49787
    亚型
    Ig Fraction
    Top Product
    Discover our top product PDCD6 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    PDCD6 (Programmed Cell Death 6 (PDCD6))
    别名
    PDCD6 (PDCD6 产品)
    别名
    pdcd6 antibody, MGC52821 antibody, MGC132114 antibody, zgc:63952 antibody, PDCD6 antibody, ALG-2 antibody, PEF1B antibody, AV299538 antibody, Alg2 antibody, MA-3 antibody, PS2 antibody, alg-2 antibody, programmed cell death 6 L homeolog antibody, programmed cell death 6 antibody, pdcd6.L antibody, pdcd6 antibody, PDCD6 antibody, Pdcd6 antibody
    背景
    Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)- regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis, the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Seems to play a role in the regulation of the distribution and function of MCOLN1 in the endosomal pathway. Isoform 2 has a lower Ca(2+) affinity than isoform 1. Isoform 1 and, to a lesser extend, isoform 2, can stabilize SHISA5.
    分子量
    21868
    UniProt
    O75340
    途径
    Positive Regulation of Endopeptidase Activity
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