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RAD9A 抗体 (C-Term)

RAD9A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB51320 unconjugated
产品编号 ABIN6242553
发货至: 中国
  • 抗原 See all RAD9A 抗体
    RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
    抗原表位
    • 22
    • 15
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    • 8
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    AA 279-313, C-Term
    适用
    • 146
    • 47
    • 22
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 158
    • 9
    • 1
    克隆类型
    • 159
    • 9
    多克隆
    标记
    • 69
    • 15
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    • 1
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    This RAD9A antibody is un-conjugated
    应用范围
    • 136
    • 82
    • 54
    • 41
    • 40
    • 29
    • 12
    • 10
    • 9
    • 7
    • 7
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    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Mouse Rad9a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 279-313 amino acids from the C-terminal region of Mouse Rad9a.
    克隆位点
    RB51320
    亚型
    Ig Fraction
    Top Product
    Discover our top product RAD9A Primary Antibody
  • 应用备注
    WB: 1:2000. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
    别名
    Rad9a (RAD9A 产品)
    别名
    RAD9 antibody, Rad9 antibody, rad9a antibody, MGC89062 antibody, XRad9 antibody, rad9 antibody, RAD9 checkpoint clamp component A antibody, RAD9 checkpoint clamp component B antibody, RAD9 checkpoint clamp component A L homeolog antibody, RAD9A antibody, Rad9a antibody, rad9a antibody, rad9b antibody, rad9a.L antibody
    背景
    Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds, endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths, and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. RAD9A possesses 3'->5' double stranded DNA exonuclease activity (By similarity).
    分子量
    42059
    UniProt
    Q9Z0F6
    途径
    Positive Regulation of Response to DNA Damage Stimulus
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