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- 抗原 See all RAB13 抗体
- RAB13 (RAB13, Member RAS Oncogene Family (RAB13))
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抗原表位
- AA 1-203
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This RAB13 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- This RAB13 antibody is generated from a mouse immunized with a recombinant protein between 1-203 amino acids from human RAB13.
- 克隆位点
- 1600CT845-37-29
- 亚型
- IgG1
- Top Product
- Discover our top product RAB13 Primary Antibody
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anti-RAB13, Member RAS Oncogene Family (RAB13) (AA 66-200) antibody
RAB13 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8E8E2 unconjugated
anti-RAB13, Member RAS Oncogene Family (RAB13) (AA 1-203) antibodyRAB13 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8H8 unconjugated
anti-RAB13, Member RAS Oncogene Family (RAB13) (AA 121-150), (C-Term) antibodyRAB13 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAB13, Member RAS Oncogene Family (RAB13) antibodyRAB13 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAB13, Member RAS Oncogene Family (RAB13) (AA 1-203) antibodyRAB13 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-RAB13, Member RAS Oncogene Family (RAB13) (AA 109-137) antibodyRAB13 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19805 unconjugated
anti-RAB13, Member RAS Oncogene Family (RAB13) (AA 91-140) antibodyRAB13 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 斑马鱼, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- RAB13 (RAB13, Member RAS Oncogene Family (RAB13))
- 别名
- RAB13 (RAB13 产品)
- 别名
- cb764 antibody, hm:zeh0455 antibody, RAB13 antibody, 0610007N03Rik antibody, B230212B15Rik antibody, RAB13, member RAS oncogene family antibody, rab13 antibody, RAB13 antibody, Rab13 antibody
- 背景
- The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in endocytic recycling and regulates the transport to the plasma membrane of transmembrane proteins like the tight junction protein OCLN/occludin. Thereby, it regulates the assembly and the activity of tight junctions. Moreover, it may also regulate tight junction assembly by activating the PKA signaling pathway and by reorganizing the actin cytoskeleton through the activation of the downstream effectors PRKACA and MICALL2 respectively. Through its role in tight junction assembly, may play a role in the establishment of Sertoli cell barrier. Plays also a role in angiogenesis through regulation of endothelial cells chemotaxis. Also involved in neurite outgrowth. Has also been proposed to play a role in post-Golgi membrane trafficking from the TGN to the recycling endosome. Finally, it has been involved in insulin- induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore may play a role in glucose homeostasis.
- 分子量
- 22774
- UniProt
- P51153
- 途径
- Cell-Cell Junction Organization
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