This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This STAG2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 61-94 amino acids from the N-terminal region of human STAG2.
Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.