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MBD2 抗体 (AA 10-228)
MBD2
适用: 人
WB, IHC (p)
宿主: 小鼠
Monoclonal
1812CT625-9-45
unconjugated
MBD2抗体详情
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抗原
See all MBD2 抗体
MBD2
(Methyl-CpG Binding Domain Protein 2 (MBD2))
抗原表位
All epitopes for MBD2 抗体
AA 10-228
适用
All reactivities for MBD2 抗体
人
宿主
All hosts for MBD2 抗体
小鼠
克隆类型
All clonalities for MBD2 抗体
单克隆
标记
All conjugates for MBD2 抗体
This MBD2 antibody is un-conjugated
应用范围
All applications for MBD2 抗体
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
纯化方法
This antibody is purified through a protein G column, followed by dialysis against PBS.
免疫原
This MBD2 antibody is generated from a mouse immunized with a recombinant protein between 10-228 amino acids from human MBD2.
克隆位点
1812CT625-9-45
亚型
IgG1 kappa
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Alternatives
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anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 151-200) antibody
MBD2
适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, Bat, 猴, Pig, 小鸡
WB
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
WB: 1:2000. IHC-P: 1:25
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
有效期
6 months
MBD2目标详情
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抗原
MBD2
(Methyl-CpG Binding Domain Protein 2 (MBD2))
别名
MBD2 (MBD2 产品 )
别名
MBD2 antibody, DMTase antibody, NY-CO-41 antibody, MBD2a antibody, wu:fa97f06 antibody, zgc:111862 antibody, methyl-CpG binding domain protein 2 antibody, methyl-CpG binding domain protein 2 S homeolog antibody, MBD2 antibody, Mbd2 antibody, mbd2 antibody, mbd2.S antibody
背景
Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
分子量
43255
UniProt
Q9UBB5
途径
Chromatin Binding
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