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PDX1 抗体 (AA 136-169)

PDX1 适用: 小鼠 WB, IF 宿主: 兔 Polyclonal RB51197 unconjugated
产品编号 ABIN6242401
发货至: 中国
  • 抗原 See all PDX1 抗体
    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
    抗原表位
    • 21
    • 15
    • 15
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 136-169
    适用
    • 115
    • 45
    • 33
    • 15
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 127
    • 8
    • 2
    克隆类型
    • 122
    • 15
    多克隆
    标记
    • 61
    • 12
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDX1 antibody is un-conjugated
    应用范围
    • 85
    • 63
    • 32
    • 20
    • 17
    • 14
    • 14
    • 11
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Mouse Pdx1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 136-169 amino acids from the Central region of Mouse Pdx1.
    克隆位点
    RB51197
    亚型
    Ig Fraction
    Top Product
    Discover our top product PDX1 Primary Antibody
  • 应用备注
    IF: 1:25. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
    别名
    Pdx1 (PDX1 产品)
    别名
    GSF antibody, IDX-1 antibody, IPF1 antibody, IUF1 antibody, MODY4 antibody, PDX-1 antibody, STF-1 antibody, ipf1 antibody, PDX1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, pdx-1 antibody, Idx1 antibody, Stf1 antibody, zgc:100874 antibody, XlHbox-8 antibody, xlhbox8 antibody, pancreatic and duodenal homeobox 1 antibody, pancreatic and duodenal homeobox 1 S homeolog antibody, PDX1 antibody, pdx1 antibody, Pdx1 antibody, pdx1.S antibody
    背景
    Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds the DNA sequence 5'-CC[CT]TAATGGG-3'.
    分子量
    30999
    UniProt
    P52946
    途径
    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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